COVID/histamine connection

Source: American Society for Microbiology JournalThis is information about what you can do if you test positive for COVID. It may improve your chances of a full recovery and lower your long COVID risk. The short version is to immediately begin taking both a h1 (Claritin, Allegra, Zyrtec) and h2 (Pepcid) antihistimine (available OTC) as soon as you test positive.

The long, recently updated version can be found on Bluesky, and the original 2023 article (COVID antihistimine protocol) can be found on Dreamwidth.org, an open-source online journaling and social networking platform. The author is one of the co-founders of Dreamwidth.

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USE THIS INFORMATION AT YOUR OWN RISK!
I am not a medical professional & I don’t play one on on TV!

I am simply sharing this information with you.
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Below are highlights of the updated info (I am both quoting and paraphrasing the Bluesky thread):

1. The underlying science behind the COVID/antihistamine link There are two major connections between the SARS-CoV-2 virus and histamine.
> The first is that the virus uses histamine receptors as a method of cell entry/replication: https://journals.asm.org/doi/10.1128/mbio.01088-24 and https://journals.asm.org/doi/10.1128/mbio.01697-24
> The second is that, once present in the body, the spike protein of SARS-CoV-2 is a potent mast cell degranulation trigger. Mast cells are a part of the immune system that perform multiple functions in fighting off infections, and mast cell dysfunctions are essentially autoimmune disorders.

Basically, the COVID virus uses histamine receptors to infect your cells, and the spike protein of the virus temporarily freaks out an important part of your immune system and makes it too busy screaming about the virus to fight the virus as effectively.

2. This underlying science results in two easy practical things you can do to make your life easier when dealing with COVID.
> Use antihistamines for COVID prevention. NOTE – VERY IMPORTANT: this is NOT a perfect preventative and should NOT be your only precaution.
> The best precaution against COVID is still wearing a well-fitting (K)N95 mask whenever you are around other people. Antihistamines should be part of a defense in depth strategy and not your only precaution.

3. H1 antihistimines: https://en.m.wikipedia.org/wiki/H1_antagonist Read the side effect info before choosing an antihistimine for your use!

READ THE BLUESKY THREAD for the details of the COVID/antihistimine protocol!!! There’s a LOT of info there that I’m not sharing here!

Here’s some additional cool info found in the Bluesky thread: You can use prophylactic antihistamines for COVID vaccination reactions, too! Taking a “rescue dose” of antihistamines before you get the vaccine will reduce the severity of the mast cell reaction. In most people without mast cell diseases, it can completely prevent problems; in others it just makes them way more tolerable. DOES NOT AFFECT VACCINE EFFICACY IN THE SLIGHTEST.

Check on Bluesky for the dosages.

As the author says, the above is not a perfect preventative; studies seem to consistently show about a 40-60% risk reduction in long COVID.

READ THE WHOLE THREAD FOR ALL THE INFO YOU NEED!  If you don’t have a Bluesky account, and don’t want to open one, use Google. Her’s a link to a ScienceDirect article about the protocol.

NOTICE: Something is wrong with WordPress and it is rejecting comments. Hopefully this will be fixed soon. 

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About lifstrand

Lif Strand began writing fiction when she was a kid. Nobody read her stories. A former Arabian horse breeder and endurance racer, then reporter and freelance white paper writer, Lif lives in a straw bale house off-the-grid and writes fiction once more--or at least whenever she’s not scooping horse poop, taking photos, or playing with fabric art.

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